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Scientists Find Key Piece in Brain Tumour Puzzle
Scientists at the Montreal Neurological Institute and Hospital, McGill University and McGill University Health Centre have shown that a member of the protein family known as SUMO (small ubiquitin-like modifier) is a key to why tumour cells multiply uncontrollably, especially in the case of glioblastoma. The SUMO family proteins modify other proteins and the SUMOylation of proteins are critical for many cellular processes. Identifying SUMO’s role in the cancer cell growth will lead to a new strategy for glioblastoma treatment.
Glioblastoma is the most common and lethal brain cancer. Current standard treatments include surgical resection, adjuvant chemotherapy and radiotherapy. Despite the treatments, patients’ survive about a year and half. The cancer continues growing in part due to the presence of the cancer stem cells. It is critical to understand cancer growing pathways in the stem cells for development of stem cells targeted therapies.
More information on Glioblastomas and surgery techniques:
I’ll miss u in the business Cassie
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